Aspartame and Other Sweeteners in Food
FDA · 2024
U.S. Food and Drug Administration
https://www.fda.gov/food/food-additives-petitions/aspartame-and-other-sweeteners-foodArtificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort
NIH (PMC) · 1 septembre 2023
Debras C., Deschasaux-Tanguy M., Chazelas E., Sellem L., Druesne-Pecollo N., Esseddik Y., et al.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465821/The dietary sweetener sucralose is a negative modulator of T cell-mediated responses
Nature · 1 mars 2023
Zani F., Blagih J., Gruber T., et al.
https://doi.org/10.1038/s41586-023-05801-6Newborns from Mothers Who Intensely Consumed Sucralose during Pregnancy Are Heavier and Exhibit Markers of Metabolic Alteration and Low-Grade Systemic Inflammation: A Cross-Sectional, Prospective Study
MDPI (Biomedicines) · 21 février 2023
Aguayo-Guerrero JA., Méndez-García LA., Manjarrez-Reyna AN., et al.
https://pubmed.ncbi.nlm.nih.gov/36979631/Biological Assessment of Stevioside and Sucralose as Sucrose Substitutes for Diabetics on STZ-Induced Diabetes in Rats
MDPI (Molecules) · 2023
Barakat H., Al-Roug K., Algonaiman R., et al.
https://doi.org/10.3390/molecules28030940Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort
BMJ · 1 septembre 2022
Debras C., Chazelas E., Sellem L., Porcher R., Druesne-Pecollo N., Esseddik Y., et al.
https://doi.org/10.1136/bmj-2022-071204Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance
Cell · 1 septembre 2022
Suez J., Cohen Y., Valdés-Mas R., Mor U., Dori-Bachash M., Federici S., et al.
https://pubmed.ncbi.nlm.nih.gov/35987213/Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study
PLOS · 24 mars 2022
Debras C., Chazelas E., Srour B., Druesne-Pecollo N., Esseddik Y., et al.
https://doi.org/10.1371/journal.pmed.1003950Low Dose of Sucralose Alter Gut Microbiome in Mice
Frontiers · 1 mars 2022
Zheng Z., Xiao Y., Ma L., Lyu W., Peng H., Wang X., et al.
https://doi.org/10.3389/fnut.2022.848392Sucralose, a Non-nutritive Artificial Sweetener Exacerbates High Fat Diet-Induced Hepatic Steatosis Through Taste Receptor Type 1 Member 3
Frontiers · 1 mars 2022
Wu H. T., Lin C. H., Pai H. L., Chen Y. C., Cheng K. P., Kuo H. Y., et al.
https://doi.org/10.3389/fnut.2022.823723Ten-Week Sucralose Consumption Induces Gut Dysbiosis and Altered Glucose and Insulin Levels in Healthy Young Adults
MDPI (Microorganisms) · 1 février 2022
Méndez-García L. A., Bueno-Hernández N., Cid-Soto M. A., et al.
https://doi.org/10.3390/microorganisms10020434Low Doses of Sucralose Alter Fecal Microbiota in High-Fat Diet-Induced Obese Rats
Frontiers · 1 novembre 2021
Zhang M., Chen J., Yang M., Qian C., Liu Y., Qi Y., et al.
https://doi.org/10.3389/fnut.2021.787055Nonnutritive sweetener consumption during pregnancy, adiposity, and adipocyte differentiation in offspring: evidence from humans, mice, and cells
Nature (International Journal of Obesity) · 1 octobre 2020
Azad M. B., Archibald A., Tomczyk M. M., et al.
https://doi.org/10.1038/s41366-020-0575-xSucralose causes non-selective CD4 and CD8 lymphotoxicity via probable regulation of the MAPK8/APTX/EID1 genes: An in vitro/in silico study
Wiley (CEPP) · 1 octobre 2020
Pasqualli T., E Chaves P. E., da Veiga Pereira L., et al.
https://doi.org/10.1111/1440-1681.13362The impact of food additives, artificial sweeteners and domestic hygiene products on the human gut microbiome and its fibre fermentation capacity
Springer (European Journal of Nutrition) · 1 octobre 2020
Gerasimidis K., Bryden K., Chen X., et al.
https://doi.org/10.1007/s00394-019-02161-8Consumption of Diet Soda Sweetened with Sucralose and Acesulfame-Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity
Wiley (Molecular Nutrition & Food Research) · 1 juin 2020
Sylvetsky A. C., Sen S., Merkel P., et al.
https://doi.org/10.1002/mnfr.201901166Artificial sweeteners impair endothelial vascular reactivity: Preliminary results in rodents
NMCD · 1 mai 2020
Risdon S., Meyer G., Marziou A., Riva C., Roustit M., Walther G.
https://doi.org/10.1016/j.numecd.2020.01.014Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial
BioMed Central (Nutrition Journal) · 1 avril 2020
Bueno-Hernández N., Esquivel-Velázquez M., Alcántara-Suárez R., et al.
https://doi.org/10.1186/s12937-020-00549-5Maternal sucralose intake alters gut microbiota of offspring and exacerbates hepatic steatosis in adulthood
Taylor & Francis (Gut Microbes) · 2020
Dai X., Guo Z., Chen D., Li L., Song X., Liu T., et al.
https://pubmed.ncbi.nlm.nih.gov/32228300/Maternal exposure to non-nutritive sweeteners impacts progeny's metabolism and microbiome
Frontiers · 2019
Olivier-Van Stichelen S., Rother K. I., Hanover J. A.
https://doi.org/10.3389/fmicb.2019.01360Sucralose decreases insulin sensitivity in healthy subjects: a randomized controlled trial
Oxford Academic (AJCN) · 1 septembre 2018
Romo-Romo A., Aguilar-Salinas C. A., Brito-Córdova G. X., et al.
https://doi.org/10.1093/ajcn/nqy152Intestinal metabolism and bioaccumulation of sucralose in adipose tissue in the rat
Taylor & Francis (JTEH) · 1 août 2018
Bornemann V., Werness S. C., Buslinger L., Schiffman S. S.
https://doi.org/10.1080/15287394.2018.1502560Type of sweet flavour carrier affects thyroid axis activity in male rats
Springer (European Journal of Nutrition) · 1 mars 2018
Pałkowska-Goździk E., Bigos A., Rosołowska-Huszcz D.
https://doi.org/10.1007/s00394-016-1367-xEffects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial
Nutrition · 2018
Lertrit A., Srimachai S., Saetung S., et al.
https://doi.org/10.1016/j.nut.2018.04.001Critical review of the current literature on the safety of sucralose
ScienceDirect (FCT) · 1 juillet 2017
Magnuson B. A., Roberts A., Nestmann E. R.
https://pubmed.ncbi.nlm.nih.gov/28558975/Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice
Frontiers · 1 juillet 2017
Bian X., Chi L., Gao B., Tu P., Ru H., Lu K.
https://doi.org/10.3389/fphys.2017.00487Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
CMAJ (via NIH/PubMed) · 1 juillet 2017
Azad M. B., et al.
https://www.ncbi.nlm.nih.gov/pubmed/28716847Effects of low-dose non-caloric sweetener consumption on gut microbiota in mice
MDPI (Nutrients) · 1 juin 2017
Uebanso T., Ohnishi A., Kitayama R., et al.
https://doi.org/10.3390/nu9060560Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute
EFSA · 1 mai 2017
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
https://doi.org/10.2903/j.efsa.2017.4784Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice
Taylor & Francis (IJOEH) · 2016
Soffritti M., Padovani M., Tibaldi E., et al.
https://doi.org/10.1016/j.fct.2017.05.047Avis du 19 novembre 2014 révisé le 9 janvier 2015 relatif à l'évaluation des bénéfices et des risques nutritionnels des édulcorants intenses
ANSES · 9 janvier 2015
Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
https://www.anses.fr/fr/system/files/NUT2011sa0161Ra.pdfArtificial sweeteners induce glucose intolerance by altering the gut microbiota
Nature (via NIH/PubMed) · 1 octobre 2014
Suez J., et al.
https://pubmed.ncbi.nlm.nih.gov/25231862/Sucralose affects glycemic and hormonal responses to an oral glucose load
Diabetes Care · 1 septembre 2013
Pepino M. Y., Tiemann C. D., Patterson B. W., Wice B. M., Klein S.
https://doi.org/10.2337/dc12-2221Studies on glucose homeostasis in healthy humans and diabetic volunteers. In: Opinion of the Scientific Committee on Food on Sucralose
Commission Européenne · 7 septembre 2000
Scientific Committee on Food (SCF)
https://food.ec.europa.eu/system/files/2020-12/sci-com_scf_out68_en.pdf