Sources scientifiques

  1. Aspartame and Other Sweeteners in Food

    U.S. Food and Drug Administration (FDA) · 2024

    U.S. Food and Drug Administration (FDA)

    https://www.fda.gov/food/food-additives-petitions/aspartame-and-other-sweeteners-food
  2. Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort

    Diabetes Care · 1 septembre 2023

    Debras C., Deschasaux-Tanguy M., Chazelas E., Sellem L., Druesne-Pecollo N., Esseddik Y., Szabo de Edelenyi F., Agaesse C., De Sa A., Lutchia R., Julia C., Kesse-Guyot E., Allès B., Galan P., Hercberg S., Huybrechts I., Cosson E., Tatulashvili S., Srour B., Touvier M.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465821/
  3. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study

    PLoS Medicine · 24 mars 2022

    Debras C., Chazelas E., Srour B., Druesne-Pecollo N., Esseddik Y., Szabo de Edelenyi F., Agaesse C., De Sa A., Lutchia R., Gigandet S., Huybrechts I., Julia C., Kesse-Guyot E., Allès B., Andreeva VA., Galan P., Hercberg S., Deschasaux-Tanguy M., Touvier M.

    https://doi.org/10.1371/journal.pmed.1003950
  4. Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort

    BMJ (British Medical Journal) · 2022

    Debras C., Chazelas E., Sellem L., Porcher R., Druesne-Pecollo N., Esseddik Y., et al.

    https://doi.org/10.1136/bmj-2022-071204
  5. Early-life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats

    JCI Insight · 2022

    Tsan L., Chometton S., Hayes A. M., Klug M. E., Zuo Y., Sun S., et al.

    https://doi.org/10.1172/jci.insight.157714
  6. Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

    Cell · 2022

    Suez J., Cohen Y., Valdés-Mas R., Mor U., Dori-Bachash M., Federici S., et al.

    https://pubmed.ncbi.nlm.nih.gov/35987213/
  7. Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa

    Journal of Gastroenterology and Hepatology · 2021

    Hanawa Y., Higashiyama M., Kurihara C., Tanemoto R., Ito S., Mizoguchi A., et al.

    https://doi.org/10.1111/jgh.15654
  8. Artificial sweeteners impair endothelial vascular reactivity: Preliminary results in rodents

    Nutrition, Metabolism and Cardiovascular Diseases · 2020

    Risdon S., Meyer G., Marziou A., Riva C., Roustit M., Walther G.

    https://doi.org/10.1016/j.numecd.2020.01.014
  9. Consumption of the artificial sweetener acesulfame potassium throughout pregnancy induces glucose intolerance and adipose tissue dysfunction in mice

    The Journal of Nutrition · 2020

    Plows J. F., Morton-Jones J., Bridge-Comer P. E., Ponnampalam A., Stanley J. L., Vickers M. H., Reynolds C. M.

    https://doi.org/10.1093/jn/nxaa106
  10. Nonnutritive sweetener consumption during pregnancy, adiposity, and adipocyte differentiation in offspring: evidence from humans, mice, and cells

    International Journal of Obesity · 2020

    Azad M. B., Archibald A., Tomczyk M. M., Head A., Cheung K. G., de Souza R. J., et al.

    https://doi.org/10.1038/s41366-020-0575-x
  11. Maternal exposure to non-nutritive sweeteners impacts progeny's metabolism and microbiome

    Frontiers in Microbiology · 2019

    Olivier-Van Stichelen S., Rother K. I., Hanover J. A.

    https://doi.org/10.3389/fmicb.2019.01360
  12. Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial

    Nutrition · 2018

    Lertrit A., Srimachai S., Saetung S., Chanprasertyothin S., Chailurkit L. O., Areevut C., et al.

    https://doi.org/10.1016/j.nut.2018.04.001
  13. Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice

    Frontiers in Physiology · 2017

    Bian X., Chi L., Gao B., Tu P., Ru H., Lu K.

    https://doi.org/10.3389/fphys.2017.00487
  14. The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice

    PLoS One · 2017

    Bian X., Chi L., Gao B., Tu P., Ru H., Lu K.

    https://pubmed.ncbi.nlm.nih.gov/28594855/
  15. Relationship between Research Outcomes and Risk of Bias, Study Sponsorship, and Author Financial Conflicts of Interest in Reviews of the Effects of Artificially Sweetened Beverages on Weight Outcomes: A Systematic Review of Reviews

    PLoS One · 8 septembre 2016

    Mandrioli D., Kearns CE., Bero LA.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015869/
  16. Avis du 19 novembre 2014 révisé le 9 janvier 2015 relatif à l'évaluation des bénéfices et des risques nutritionnels des édulcorants intenses (Saisine n°2011-SA-0161)

    ANSES · 9 janvier 2015

    Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)

    https://www.anses.fr/fr/system/files/NUT2011sa0161Ra.pdf
  17. Artificial sweeteners induce glucose intolerance by altering the gut microbiota

    Nature · 2014

    Suez J., Korem T., Zeevi D., Zilberman-Schapira G., Thaiss CA., Maza O., et al.

    https://pubmed.ncbi.nlm.nih.gov/25231862/
  18. Fueling the Obesity Epidemic? Artificially Sweetened Beverage Use and Long-term Weight Gain

    Obesity · 2008

    Fowler S.P., Williams K., Resendez R.G., Hunt K.J., Hazuda H.P., Stern M.P.

    https://doi.org/10.1038/oby.2008.284
  19. Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin

    Drug and Chemical Toxicology · 2008

    Bandyopadhyay A., Ghoshal S., Mukherjee A.

    https://doi.org/10.1080/01480540802390270
  20. In vivo cytogenetic studies on mice exposed to acesulfame-K - a non-nutritive sweetener

    Food and Chemical Toxicology · 1997

    Mukherjee A., Chakrabarti J.

    https://doi.org/10.1016/s0278-6915(97)85469-5